Articles

Pathoprofile: Alzheimer’s

Alzheimer’s disease is an age-related neurodegenerative disorder characterized by gradual cognitive decline. With 44 million people affected worldwide, it is one society’s most prevalent degenerative diseases. The number of Canadians suffering from Alzheimer’s or a related…




Circulating Tumor DNA for Cancer Prognostication

Nasopharyngeal carcinoma (NPC) is a squamous cancer of the head and neck which affects the nasopharyngeal epithelium. Since NPC cells express Epstein-Barr Viral (EBV) genes, a double-stranded DNA herpes virus, its tumours release circulating tumour…



S1PR1 Modulator and Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disorder that destroys the myelin sheath, a critical insulator surrounding axons, in the central nervous system. While MS affects more than 2.3 million individuals globally, current therapeutic options are…


CRISPR Goes Viral

In the 1980s, scientists discovered that bacterial genomes held arrays of repeating DNA sequences with unique intermittent strings of viral DNA. They named this configuration Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and later found…


Study Finds New Route of Zika Virus Transmission

Heavily featured in recent news for its rapid spread through South America, Zika is a mosquito-borne virus with no established vaccine or prevention methods. Although Zika contraction is often characterized by little to no symptoms,…


Star-Shaped Peptide Polymers Kill Superbugs

Antibacterial resistance poses an enormous threat to the ability to treat common diseases. It occurs when bacteria develop genetic mutations that render antibiotic drugs ineffective, resulting in prolonged hospital stays and high mortality rates. Multi-drug…