The biohacking movement was catapulted into mainstream attention when AIDS patient Tristan Roberts livestreamed a self-injection with an untested gene therapy vector.1 Biohacking, also known as Do-It-Yourself Biology, is the technological manipulation of biological systems […]
Maternal obesity is associated with increased risk of offspring metabolic dysfunction in adulthood. Lipotoxicity, a metabolic syndrome, has been linked with gluconeogenic changes in clinical and animal studies. The impact of maternal obesity on fetal […]
The placenta is involved in the transport and exchange of gases, nutrients, and waste products at the mother-fetus interface. During the early stages of pregnancy, trophoblasts, the primary stem cell lineage in the placenta, play […]
Introduction Pain is an essential sensation that has developed in complex organisms as an evolutionary mechanism to signal impending danger. Without pain, day-to-day functions become incredibly compromised. Pain is responsible for triggering the adoption of […]
Diabetes mellitus (DM), a metabolic disorder characterized by irregular insulin production or insulin resistance, affects over 350 million people worldwide.1 Diabetic individuals must monitor their blood glucose levels several times a day, using a process […]
Internationally, more than 700,000 people die from antimicrobial-resistant bacterial diseases each year.1 With superbugs developing resistance to even the antibiotic of last resort, vancomycin, scientists are racing to expand options. Currently, research is investigating the […]
The immune system is naturally programmed to target and attack tumours using T lymphocytes. As tumours grow, however, they can inhibit immune cells and escape immune detection, creating an internal reservoir of inhibited T cells.1 […]
Despite the myriad of contraceptive methods designed for women, the options for men have generally relied on vasectomy or use of condoms.1 Recently, however, researchers from the American Chemical Society have investigated the potential of […]
Dr. Yingfu Li is a Professor of Biochemistry and Biomedical Sciences at McMaster University, an associate editor of the Journal of Molecular Evolution, and is a Canada Research Chair in nucleic acids research. His work explores […]
A modern definition of “species” focuses on a shared gene pool and reproductive ability. Based on this definition, in order to determine what mutations give rise to new species, we should consider what mutations cause […]
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