Adverse childhood experiences: A public health challenge

August 1, 2018 0

Access Full Text INTRODUCTION The life-course approach to health and the critical period model of disease causation posit that adult health is shaped by experiences in early life, specifically during critical developmental periods.1 Adverse Childhood […]

Biohacking: The next scientific revolution?

August 1, 2018 0

The biohacking movement was catapulted into mainstream attention when AIDS patient Tristan Roberts livestreamed a self-injection with an untested gene therapy vector.1 Biohacking, also known as Do-It-Yourself Biology, is the technological manipulation of biological systems […]

AMPK regulates extravillous trophoblast invasion

August 1, 2018 0

The placenta is involved in the transport and exchange of gases, nutrients, and waste products at the mother-fetus interface. During the early stages of pregnancy, trophoblasts, the primary stem cell lineage in the placenta, play […]

Congenital insensitivity to pain

August 1, 2018 0

Introduction Pain is an essential sensation that has developed in complex organisms as an evolutionary mechanism to signal impending danger. Without pain, day-to-day functions become incredibly compromised. Pain is responsible for triggering the adoption of […]

Diabetes — Blood, sweat, and tears

August 1, 2018 0

Diabetes mellitus (DM), a metabolic disorder characterized by irregular insulin production or insulin resistance, affects over 350 million people worldwide.1 Diabetic individuals must monitor their blood glucose levels several times a day, using a process […]

Unearthing new antibiotics

July 31, 2018 0

Internationally, more than 700,000 people die from antimicrobial-resistant bacterial diseases each year.1 With superbugs developing resistance to even the antibiotic of last resort, vancomycin, scientists are racing to expand options. Currently, research is investigating the […]

A new promise in cancer immunotherapy

July 31, 2018 0

The immune system is naturally programmed to target and attack tumours using T lymphocytes. As tumours grow, however, they can inhibit immune cells and escape immune detection, creating an internal reservoir of inhibited T cells.1 […]

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